Retrotransposon drives cancer by altering 3D genome structure

Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE ...

Genentech enters $100M deal with Structure Therapeutics for GLP-1 weight-loss drug

Structure Therapeutics' (GPCR) subsidiary Gasherbrum Bio signed a patent license agreement with Genentech, granting Genentech ...
eLife

PKD2L1 channels segregated to the apical compartment are the exclusive dual-mode pH sensor in cerebrospinal fluid-contacting neurons

This is an important study on the sensory roles of Cerebrospinal fluid-contacting neurons (CBF-cn) in mammals. The authors identify PKD2L1 as the predominant pH-sensing channel CBF-cn and show how the ...

Schizophrenia and osteoporosis share 195 genetic loci, highlighting unexpected biological bridges between brain and bone

A comprehensive genetic investigation led by Dr. Feng Liu at Tianjin Medical University General Hospital has uncovered ...