This illustration summarizes how integrated spatial transcriptomics, single-cell transcriptomics, single-cell epigenomics, and spatial epigenomics enable multi-dimensional profiling of the tumor ...
Researchers in Nikolaus Rajewsky’s lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor’s cellular neighborhoods in 3D and identify potential targets ...
Immune low-response states significantly impact the effectiveness of immunotherapy in cancer treatment. These states ...
Hosted on MSN
3D spatial mapping of tumor cell 'neighborhoods' reveals potential targets for personalized cancer therapy
Researchers in Nikolaus Rajewsky's lab at Max Delbrück Center combined high-resolution, single-cell spatial technologies to map a tumor's cellular neighborhoods in 3D and identify potential targets ...
Spatial biology is reshaping how researchers study cancer by revealing the architecture and complexity of tumors in extraordinary detail. Through techniques that combine protein- and gene-level ...
Exploring biology in its native environment is perhaps the ideal scenario for generating better hypotheses about the cellular interactions that influence—and drive—healthy and diseased states, ...
Hosted on MSN
AI indelibly transforms solid tumor drug development
Artificial intelligence (AI) is fundamentally reshaping the landscape of solid tumor (ST) drug development. By integrating multi-omics data, spatial transcriptomics, and advanced computational models, ...
Scientists have identified a new CAF subset in HNSCC using tissue cytometry and spatial transcriptomics. In two-thirds of cases, head and neck squamous cell carcinomas (HNSCC) require treatment with ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results