A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...

Dissociating tissues into single cells is a core laboratory technique and vital for widely used applications such as next-generation sequencing or flow cytometry. Scientists who employ tissue ...

Hidden inside every organ, microscopic fibers form a scaffolding that quietly shapes how we move, think, and heal. For the ...

Nucleic acid extraction from biological samples is inherently difficult to execute consistently across different tissue types. Some tissue matrices are fibrous, contained in protective cell walls, or ...

Shedding pounds almost invariably brings health benefits. But until now, it has been unclear to what extent weight loss also ...

Cryo-electron tomography (cryo-ET) can provide invaluable insights into subcellular structures in their native environment at molecular resolution. Cryo-focused ion beam (cryo-FIB) has been widely ...