Leucoplast pyruvate kinase ($\text{PK}_{\text{p}}$; EC 2.7.1.40) from endosperm of developing castor oil seeds (Ricinus communis L. cv Baker 296) appears to be highly susceptible to limited ...
The development of new therapeutics targeting protein kinases is crucial in the fight against diseases like cancer.
Results from a phase 3 clinical indicate that the oral drug mitapivat is safe and effective for treating adults with pyruvate kinase deficiency, a genetic condition that causes red blood cell ...