A protein structure comparison between PBSase (pink gold backbone) and PET degrading enzyme PET6 (cobalt backbone). The catalytic centers are indicated by magenta and green. PET binding residues of ...
With MassiveFold, scientists have unlocked AlphaFold's full potential, making high-confidence protein predictions faster and more accessible, fueling breakthroughs in biology and drug discovery. Brief ...
On Wednesday, the Nobel Committee announced that it had awarded the Nobel Prize in chemistry to researchers who pioneered major breakthroughs in computational chemistry. These include two researchers ...
The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond their ...
When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...
Giving Structure to Language: Profluent’s AI Models Move toward Precise and Steerable Protein Design
The “ChatGPT moment” for biology proceeds to unfold as protein language models, or machine learning tools trained on large databases of protein sequences, work to decode the language of life with the ...
In the wee hours of an October morning, David Baker, a protein biologist at the University of Washington (UW), received the most-awaited phone call in a scientist’s career. Halfway around the world, ...
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