In Alzheimer’s disease, proteins in the brain pile up in plaques and tangles. Could the proteome yield clues on how that happens that genomic and transcriptomic studies miss? In today’s Nature ...

Cryo-EM and method development, Microbial conductive nanowires, Self-assembled nanotube design. Large protein assemblies in nature are universal and essential. They represent a unique gold mine to ...

More than any other biofluid, the cerebrospinal fluid is in intimate contact with the brain. What can the thousands of proteins churning within this brain bath tell us about how Alzheimer’s develops, ...

In Alzheimer's research, one particular protein looms large: plaque-forming amyloid-beta. Yet doctors now recognize that plaques can accumulate decades before symptoms appear. Recent clinical trials ...

With one of the largest segments of the population settling into prime Alzheimer’s disease (AD) age ranges, it is essential, now more than ever, to identify new biomarkers and treatment targets for ...