Animal development consists of a cascade of tissue differentiation and shape change. Associated mechanical signals regulate tissue differentiation. Here we demonstrate that endogenous mechanical cues ...

Corals first appeared on earth nearly half a billion years ago during the Cambrian Period of the Paleozoic Era. The ancient Greek philosopher Aristotle categorized corals as zoophyta, or ...

In a study of over 50 transcription factors, Tbx6 alone was able to stimulate mesoderm formation in laboratory-grown stem cells, and could cause those stem cells to become cardiovascular or ...

Research from Ph.D. candidate Bohan Chen in the lab of Idse Heemskerk of the Department of Cell and Developmental Biology at the University of Michigan Medical School and their colleagues improves ...

Tsukuba, Japan - Many studies have attempted to identify a single transcription factor that can induce formation of mesoderm, an early layer in embryonic development, without help from other cellular ...