Organoids refer to small-scale organs made up of diverse cell types, exhibiting structures and functions akin to actual organs. Unlike conventional cell cultures, organoids better replicate human ...

Mitochondrial respiratory complexes (Complexes I–V) and their assembly into respiratory supercomplexes (SCs) are fundamental to liver bioenergetics, redox homeostasis, and metabolic adaptability.

Fatty liver disease isn’t just a concern for the overweight—it can strike people of healthy weight and diet, and now scientists think they know why. Two genes previously linked to cancer, RNF43 and ...

Scientists have discovered that blocking a key cellular enzyme thought to protect against fatty liver disease may instead ...

Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified an effective strategy to reduce structural liver damage and improve hepatic vascular function in cirrhosis. The ...

A study reveals advances in the understanding and treatment of liver fibrosis, a serious complication in the context of metabolic fatty liver disease, also known as MASLD (metabolic ...

With smart DMPK strategies, cross-domain collaboration, and strong CDMO support, companies are pushing past the challenges of ...

The liver is accountable for metabolizing most medications and is therefore one of the primary tissues affected by adverse drug reactions. Most classes of medicine can cause drug-induced liver injury ...

Recent research suggests that a new approach could help even patients with advanced forms of fatty liver disease. By Nina Agrawal Nearly four in 10 American adults are estimated to have a liver ...