Challenges and Prospects. Challenges and prospects faced by spatial transcriptomics itself and its application to the musculoskeletal system. AI Artificial intelligence, FFPE Formalin fixed and ...

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...

Spatial transcriptomics is a technique that provides information about gene expression patterns within intact tissues. This technology employs various methodologies, including in situ sequencing (ISS) ...

Illumina is raising the curtain on its upcoming entry into spatial transcriptomics, with tech designed to help researchers explore cellular behavior mapped across complex tissues. The announcement ...

Spatial biology is reshaping how researchers study cancer by revealing the architecture and complexity of tumors in extraordinary detail. Through techniques that combine protein- and gene-level ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

In the rapidly developing field of spatial biology, researchers are working to expand our understanding of biological processes within their spatial context. Scientists are taking a holistic approach ...

Researchers have demonstrated the feasibility of a morphological-based approach to interpreting spatial transcriptomic (ST) data, helping to improve understanding of the lesions that occur in chronic ...

Many spatial biology researchers rely on two-dimensional tools, which section the cellular architecture and processes occurring within 3D tissues into flat layers. Three-dimensional multiomic analysis ...

How do plants regenerate roots from scratch after being wounded? In this study, scientists used spatial transcriptomics and time-series gene expression analysis to trace poplar root regeneration from ...