Copper chelation shows promising results in certain lung cancers where cells have two related phenomena: a heightened transcription factor responding to oxidative stress and a diminished level of ...
The Chang Lab at Princeton Chemistry continues in its mission to elucidate the role of metal nutrients in human biology: last year, iron; this year, copper. The lab's first paper of 2025 showcases its ...
The Chris Chang Lab develops a revelatory sensing probe for the detection of copper in human cells and then wields it to uncover how copper may be regulating cell growth in lung cancer. The Chang Lab ...
Schematic detailing the design strategy for the histochemical activity-based sensing of labile Cu(I) pools. Credit: Chang Lab The Chang Lab at Princeton Chemistry continues in its mission to elucidate ...