The BCL-2–family protein BAK is responsible for mitochondrial outer-membrane permeabilization (MOMP), which leads to apoptosis. The BCL-2 homology 3 (BH3)-only protein BID activates BAK to perform ...
Each of the Bcl-2 proteins is unique, having distinct molecular properties, biological activities, localization and ligand binding specificities that reflect their specific biological roles. Here we ...
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