Spray-drying is a preferred process for manufacturing amorphous solid dispersions, which provide oral bioavailability enhancement for low-solubility small molecules. High permeability, low-solubility ...
Weighing the pros and cons of hot-melt extrusion and spray drying. The oral route remains the most preferred method for delivering drugs. It offers good patient compliance due to its acceptability, ...
Raman imaging and scanning electron microscopy (SEM) was used to investigate acetaminophen solid dispersions prepared by hot melt extrusion (HME). This experiment confirmed that a high screw speed ...
Recent work by a team of researchers at Queen’s University Belfast and University College London has reported on a newly developed strategy for the manufacture of a high drug loaded amorphous solid ...
Recent work by a team of researchers at Queen’s University Belfast and University College London has reported on a newly developed strategy for the manufacture of a high drug loaded amorphous solid ...